Institute of Molecular Chemical Biology

RESEARCH

Institute supports the development of innovative medicine in Guangdong-Hong Kong-Macao Greater Bay Area (GBA)
Improve the development level and comprehensive strength of the life and health industry in the Greater Bay Area of Guangdong, Hong Kong and Macao

Areas of Focus Latest In Research

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Ge Yun Research Group:Engineered Cellular Vesicles Displaying Glycosylated Nanob...

Immune checkpoint blockade targeting the CD47/SIRPα axis represents an alluring avenue for cancer immunotherapy. However, the compromised efficacy and...

122024·08

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Tang Xiaoyu research group:Rule-based omics mining reveals antimicrobial macrocy...

Antimicrobial resistance remains a significant global threat, driving up mortality rates worldwide. Ribosomally synthesized and post-translationally m...

222024·06

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Wu Yundong Research Group: Catalytic glycosylation for minimally protected donor...

Oligosaccharides have myriad functions throughout biological processes1,2. Chemical synthesis of these structurally complex molecules facilitates inve...

192024·06

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Tang Xiaoyu&Ge Yun research group:A Semisynthesis Platform for the Efficient Pro...

A platform has been established for the exploration of didemnin-based drugs, combining microbial synthesis of didemnin B through genetic engineering o...

042024·02

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Tang Xiaoyu Research Group:Unveiling a CAAX Protease-Like Protein Involved in Di...

The assembly line biosynthesis of the powerful anticancer-antiviral didemnin cyclic peptides is proposed to follow a prodrug release mechanism in Tris...

212023·12

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Ge Yun Research Group:O-GlcNAcylation determines the translational regulation an...

YTHDF family members are ‘readers’ of a common mRNA modification, but their effects on mRNA translation and stability have been disputed. A new study ...

162023·11

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