Elucidation of genes enhancing natural product biosynthesis through co-evolution analysis

Rule-based omics mining reveals antimicrobial macrocyclic peptides against drug-resistant clinical isolates

Unveiling a CAAX Protease-Like Protein Involved in Didemnin Drug Maturation and Secretion

A Semisynthesis Platform for the Efficient Production and Exploration of Didemnin-Based Drugs

8. Xuexue Chang, Fangqing Zhang, Shibo Zhu, Zhuang Yang, Xiaoming Feng,* Yangbin Liu,* Photoredox-catalyzed diastereoselective dearomative prenylation and reverse-prenylation of electron-deficient indole derivatives, Nat. Commun. 2023, 14, 3876−3888.

7. Yang Xu, Hongkai Wang, Zhuang Yang, Yuqiao Zhou, Yangbin Liu,* Xiaoming Feng,* Stereodivergent Total Synthesis of Rocaglaol Initiated by Synergistic Dual-metal-catalyzed Asymmetric Allylation of Benzofuran-3(2H)-one, Chem, 2022, 8, 2011−2022. (ESI Highly Cited Paper)

6. Hongkai Wang, Yang Xu, Fangqing Zhang, Yangbin Liu,* Xiaoming Feng,* Bimetallic Palladium/ Cobalt Catalysis for Enantioselective Allylic C-H Alkylation via a Transient Chiral Nucleophile Strategy, Angew. Chem. Int. Ed. 2022, 61, e202115715. (Hot Paper, Featured in Org. Chem. Highlights)

5. Wei Wang, Fangqing Zhang, Yangbin Liu,* Xiaoming Feng,* Diastereo-and Enantioselective Construction of Vicinal All-Carbon Quaternary Stereocenters via Iridium/Europium Bimetallic Catalysis, Angew. Chem. Int. Ed. 2022, 61, e202208837. (Hot Paper, Featured in Org. Chem. Highlights)

4. Zhenda Tan, Shibo Zhu, Yangbin Liu*, Xiaoming Feng,* Photoinduced Chemo-, Site- and Stereoselective α-C(sp3)−H Functionalization of Sulfides, Angew. Chem. Int. Ed. 2022, 61, e202203374.

3. Yangbin Liu, Xiaohua Liu, Xiaoming Feng,* Recent Advances in Metal-Catalysed Asymmetric Sigmatropic Rearrangements, Chem. Sci. 2022, 13, 12290−12308.

2. Fangqing Zhang, Bing-Tao Ren, Yuqiao Zhou, Yangbin Liu,* Xiaoming Feng,* Enantioselective Construction of cis-Hydroindole Scaffolds via an Asymmetric Inverse-electron-demand Diels–Alder reaction: Application to the Formal Total Synthesis of (+)-Minovincine, Chem. Sci. 2022, 13, 5562–5567. (Hot Article)

1. Fangqing Zhang, Bing-Tao Ren, Yangbin Liu,* Xiaoming Feng,* A Nickel(II)-Catalyzed Enantioselective All-Carbonbased Inverse-Electron-Demand Diels–Alder Reaction of 2-Pyrones with Indenes, Org. Chem. Front. 2022, 9, 3956−3960. (Hot Article)

Hao-Yuan Liu, Zhen-Yu Zhang, Yi-Ke Zhou, Jia-Hua Chen, Zhen Yang,* and Yuan-He Li*, Synthesis towards Phainanoid F: Photo-induced 6π-Electrocyclization for Constructing Contiguous All-Carbon Quaternary Centers, Chem Asian J.2023,18, e20230062

Shu-Min Lu, Chao Chen, Chang Liu, Rudong Liu, Jia-Hua Chen,* Zhongchao Zhang,* and Zhen Yang*, Regioselective Hydroxylation of Flavonoids by Transition-Metal-Catalyzed C–H Bond Oxidation, Org. Lett. 2023, 25(13), 2264–2269

Yuan-He Li, Su-Lei Zhang, Yong Lu, Bo Xiao, Tian-Yu Sun, Qian-Qian Xu, Jia-Hua Chen,* Zhen Yang*, Highly Stereoselective Diels–Alder Reactions Catalyzed by Diboronate Complexes, Angew. Chem. Int. Ed. 2023, 62(33)

Zhongchao Zhang, Zhen Yang *, Recent advances in total synthesis of natrual products containing contiguous all carbon quaternary stereocenters, SCIENTIA SINICA Chimica 2023, 53(3), 277-288

Hai-Xin Yu, Nan Zheng, Chi-Tai Yeh, Chien-Ming Lee, Qi Zhang, Wen-Lv Zheng, Qing Chang, Yuan-He Li, Yu-Jun Li, Gui-Zhen Wu∗, Jun-Min Quan∗, Lin-Qi Zhang∗, Yew-Min Tzeng∗ and Zhen Yang∗, Identification and semisynthesis of (−)-anisomelic acid as oral agent against SARS-CoV-2 in mice, National Science Review 2022, 9(11), nwac 176

Anding Li, Nan Zheng, Kai Guo, Zhongchao Zhang and Zhen Yang*, Electrocatalytic Isomerization of Allylic Alcohols: Straightforward Preparation of β-Aryl-Ketones, Catalysts 2022, 12(3), 333

Jun Huang,* Tingting Cao, Zhongchao Zhang, and Zhen Yang*, Semisynthesis of (−)-Bufospirostenin A Enabled by Photosantonin Rearrangement Reaction, J. Am. Chem. Soc. 2022, 144,(6), 2479–2483

Tingting Cao, Lei Zhu,* Jun Huang,* and Zhen Yang*, Palladium-Catalyzed Intramolecular Diarylation of 1,3-Diketone in Total Synthesis of (±)-Spiroaxillarone A, Org. Lett. 2022, 24,(7), 1491–1495

Lijie Zhang, Rongya Wang, Chao Wang, Bingyan Liu, Jinfeng Yang, Zhongchao Zhang, Jun Huang,*and Zhen Yang*, Concise Synthesis of 7-Deoxypsammaplysins K and O and 7-Deoxyceratinamide A by 1,3-Dipole Cycloaddition, Org. Lett. 2022, 24(21), 3786–3791