Elucidation of genes enhancing natural product biosynthesis through co-evolution analysis

Rule-based omics mining reveals antimicrobial macrocyclic peptides against drug-resistant clinical isolates

Unveiling a CAAX Protease-Like Protein Involved in Didemnin Drug Maturation and Secretion

A Semisynthesis Platform for the Efficient Production and Exploration of Didemnin-Based Drugs

Y. Zhang#, G. Liao#, M. Wang#, Z. Zhang#, L. Liu, Y. Song, D. Wang, T. Hao, J. Feng, B. Xia, Y. Wang, X. Tang*, Y. Chen*. Human-associated bacteria adopt an unusual route for synthesizing 3-acetylated tetramates for environmental adaptation. Microbiome Accepted

Y. Zhang#, G. Liao#, M. Wang#, Z. Zhang#, L. Liu, Y. Song, D. Wang, T. Hao, J. Feng, B. Xia, Y. Wang, X. Tang*, Y. Chen*. Human-associated bacteria adopt an unusual route for synthesizing 3-acetylated tetramates for environmental adaptation. Microbiome Accepted

Y Yin#, WTC Lee, D Gupta, …, E Rothenberg#, A basal-level activity of ATR links replication fork surveillance and stress response, Mol. Cell 2021, 81, 4343-4257 (#corresponding author).

B. R. Terlouw, … X. Tang … T. Weber*, M. H. Medema*. MIBiG 3.0: a community-driven effort to annotate experimentally validated biosynthetic gene clusters. Nucleic Acids Research 2023, 51(D1): D603-D610

B. R. Terlouw, … X. Tang … T. Weber*, M. H. Medema*. MIBiG 3.0: a community-driven effort to annotate experimentally validated biosynthetic gene clusters. Nucleic Acids Research 2023, 51(D1): D603-D610

WTC Lee, Y Yin, M Morton, …, E Rothenberg, Single-molecule imaging reveals replication fork coupled formation of G-quadruplex structures hinders local replication stress signaling, Nat. Commun. 2021, 12, 1-14.

G. Liao, C. Mi, L. Yang, H. Zhang, X. Ding, M. Cai, H. Wang, W. Mei*, H. Dai*, X. Tang*. Para-quinone methide-mediated nonenzymatic formation of chalcane-containing dimers in dragon’s blood. Organic Letters 2022, 24(50): 9275–9280

G. Liao, C. Mi, L. Yang, H. Zhang, X. Ding, M. Cai, H. Wang, W. Mei*, H. Dai*, X. Tang*. Para-quinone methide-mediated nonenzymatic formation of chalcane-containing dimers in dragon’s blood. Organic Letters 2022, 24(50): 9275–9280

Y Yin#, WTC Lee, E Rothenberg#, Ultrafast data mining of molecular assemblies in multiplexed high-density super-resolution images, Nat. Commun. 2019, 10, 119 (#corresponding author).

M. Cai and X. Tang*. Human archaea and associated metabolites in health and disease. Biochemistry 2022, 61(24): 2835–2840

M. Cai and X. Tang*. Human archaea and associated metabolites in health and disease. Biochemistry 2022, 61(24): 2835–2840

Hao-Yuan Liu, Zhen-Yu Zhang, Yi-Ke Zhou, Jia-Hua Chen, Zhen Yang,* and Yuan-He Li*, Synthesis towards Phainanoid F: Photo-induced 6π-Electrocyclization for Constructing Contiguous All-Carbon Quaternary Centers, Chem Asian J.2023,18, e20230062

Shu-Min Lu, Chao Chen, Chang Liu, Rudong Liu, Jia-Hua Chen,* Zhongchao Zhang,* and Zhen Yang*, Regioselective Hydroxylation of Flavonoids by Transition-Metal-Catalyzed C–H Bond Oxidation, Org. Lett. 2023, 25(13), 2264–2269

Yuan-He Li, Su-Lei Zhang, Yong Lu, Bo Xiao, Tian-Yu Sun, Qian-Qian Xu, Jia-Hua Chen,* Zhen Yang*, Highly Stereoselective Diels–Alder Reactions Catalyzed by Diboronate Complexes, Angew. Chem. Int. Ed. 2023, 62(33)

Zhongchao Zhang, Zhen Yang *, Recent advances in total synthesis of natrual products containing contiguous all carbon quaternary stereocenters, SCIENTIA SINICA Chimica 2023, 53(3), 277-288

Y. Zhang#, G. Liao#, M. Wang#, Z. Zhang#, L. Liu, Y. Song, D. Wang, T. Hao, J. Feng, B. Xia, Y. Wang, X. Tang*, Y. Chen*. Human-associated bacteria adopt an unusual route for synthesizing 3-acetylated tetramates for environmental adaptation. Microbiome Accepted

B. R. Terlouw, … X. Tang … T. Weber*, M. H. Medema*. MIBiG 3.0: a community-driven effort to annotate experimentally validated biosynthetic gene clusters. Nucleic Acids Research 2023, 51(D1): D603-D610

G. Liao, C. Mi, L. Yang, H. Zhang, X. Ding, M. Cai, H. Wang, W. Mei*, H. Dai*, X. Tang*. Para-quinone methide-mediated nonenzymatic formation of chalcane-containing dimers in dragon’s blood. Organic Letters 2022, 24(50): 9275–9280

M. Cai and X. Tang*. Human archaea and associated metabolites in health and disease. Biochemistry 2022, 61(24): 2835–2840